The Progress of Research on Genetic Factors of Recurrent Pregnancy Loss

Figure 2

(a) Robertsonian translocations on non-homologous chromosomes. (b) Possible gametes in patients with robertsonian translocations. Non-homozygous robertsonian translocations can produce six types of gametes in the formation of germ cells, one normal, one balanced, and the remaining four unbalanced gametes. Normal and balanced gamets are designated by green border, and unbalanced gametes are designated by red border. The probability of normal and robertsonian translocation carrier are both 1/8.

(a)

(b)