Identification of Potential Biomarkers of Septic Shock Based on Pathway and Transcriptome Analyses of Immune-Related Genes

Table 2

Key genes in enriched KEGG pathways.

Pathways	Genes
KEGG_CELL_ADHESION_MOLECULES_CAMS	CD8A; HLA-DPA1; HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA
KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION	CD8A; HLA-DPA1; HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY	ZAP70; MAPK14; CD8A; CD247; CD3D; CD3E; CD3G; LCK; PRKCQ; ITK; LAT; FYN; HLA-DRA
KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION	HLA-DRA
KEGG_TYPE_I_DIABETES_MELLITUS	HLA-DPA1; HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA
KEGG_AUTOIMMUNE_THYROID_DISEASE	HLA-DPA1; HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA
KEGG_ALLOGRAFT_REJECTION	HLA-DPA1; HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA
KEGG_GRAFT_VERSUS_HOST_DISEASE	HLA-DPA1; HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA
KEGG_PRIMARY_IMMUNODEFICIENCY	ZAP70; CD8A; CD3D; CD3E; LCK
KEGG_VIRAL_MYOCARDITIS	HLA-DPA1; HLA-DPB1;HLA-DQA1;HLA-DQB1;FYN;HLA-DRA

KEGG, Kyoto Encyclopedia of Genes and Genomes.