Clinical Significance and Functional Insights of Tesmin in Hepatocellular Carcinoma

Table 1

Expression of tesmin protein in enrolled patients.

Variables	Cases	Tesmin expression		value
	(n = 128)	Low (n = 54)	High (n = 74)
Age
<50 yrs	76	31	45	0.699
≥50 yrs	52	23	29
Sex
Female	33	11	22	0.232
Male	95	43	52
HBV infection
Negative	41	21	20	0.155
Positive	87	33	54
AFP level
<400 ng/mL	44	21	23	0.358
≥400 ng/mL	84	33	51
Lesion number
Single	90	40	50	0.426
Multiple	38	14	24
Tumor size
<5.0 cm	76	47	29	<0.001
≥5.0 cm	52	7	45
Tumor side
Unilateral	113	48	65	0.855
Bilateral	15	6	9
Pathological grade
Grade 1-2	91	42	49	0.154
Grade 3	37	12	25
Histological differentiation
Well/moderate	64	22	43	0.073
Poor/undifferentiated	64	32	32
Resection margin
≥1.0 cm	44	17	27	0.556
<1.0 cm	84	37	47
Portal vein invasion
Negative	96	49	47	<0.001
Positive	32	5	27
TNM stage
TNM I-II	57	32	25	0.004
TNM III-IV	71	22	49

Note. Statistically significant by Pearson Chi-square test or Fisher’s exact test.