Possible Involvement of Smad Signaling Pathways in Induction of Odontoblastic Properties in KN-3 Cells by Bone Morphogenetic Protein-2: A Growth Factor to Induce Dentin Regeneration
Figure 1
(a) Viability of KN-3 cells after exposure to BMP-2. Data are expressed as the mean ± standard deviation of triplicate cultures. Each experiment was performed 3 times, with similar results obtained in each. (b) Phase-contrast microphotographs of KN-3 cells treated with BMP-2 (100 ng/mL) for 72 hours. (c) Alkaline phosphatase activity of KN-3 cells treated with BMP-2 (100 ng/mL). BMP-2 was replaced with fresh medium every 3 days.
