Human Calmodulin-Like Protein CALML3: A Novel Marker for Normal Oral Squamous Mucosa That Is Downregulated in Malignant Transformation
Figure 3
H&E (a) and CALML3 immunostained (b) sections of invasive squamous cell carcinoma with focal area of benign squamous mucosa under low power light microscopy (40x) and H&E (c) and CALML3 immunostained (d) sections of invasive squamous cell carcinoma with focal area of benign squamous mucosa under high power light microscopy (200x). Areas of invasive squamous cell carcinoma show a marked decrease in immunoreactivity ((b) and (d), left side of panels). Areas of intact benign oral mucosa maintain CALML3 expression with notable immunoreactivity (upper right in (c) and (d)).
