Lymphangiogenesis in Oral Squamous Cell Carcinoma: Correlation with VEGF-C Expression and Lymph Node Metastasis

Table 2

Assessment of VEGF-C expression.

	Positive LN OSCC		Negative LN OSCC		p value	95% CI	SE of difference
	Mean	SD	Mean	SD
(I) IHC (area percent)	22.23	2.228	8.63	1.818	0.00001	12.55 to 14.65	0.53
(I.1) Total expression
(I.2) Epithelial expression	10.93	1.53	4.05	1.85	0.0002	6.00 to 7.76	0.44
(I.3) Stromal expression	4.42	1.54	2.55	0.61	0.0356	1.26 to 2.48	0.30
(II) IHC (optical density)	57.1	0.339	43.5	2.66	0.001	12.62 to 14.58	0.49
(III) RT-PCR	4.486	1.86	2.239	0.785	0.0002	1.179 to 3.31	0.52