Research Article
Diagnostic Value of Cytokeratin 17 during Oral Carcinogenesis: An Immunohistochemical Study
Table 4
Association between CK17 expression and clinicopathologic parameters of patients with OSCC.
| | Clinicopathologic parameters | No. of patients (%) | 0 | 1 | Score | 2 | 3 | value |
| | Agea | | ≤60 | 50 (60.2) | 5 | 19 | | 14 | 12 | 0.7036 | | >60 | 33 (39.8) | 4 | 13 | | 9 | 7 |
| | Sexa | | Male | 50 (60.2) | 5 | 21 | | 15 | 9 | 0.3456 | | Female | 33 (39.8) | 3 | 11 | | 10 | 9 |
| | Localizationa | | Tongue | 42 (50.6) | 2 | 17 | | 13 | 10 | 0.3641 | | Nontongue | 41 (49.4) | 6 | 15 | | 12 | 8 |
| | Clinical stageb | | Stages 1 + 2 | 24 (35.3) | 3 | 10 | | 6 | 5 | 0.4789 | | Stages 3 + 4 | 44 (64.7) | 4 | 15 | | 15 | 10 |
| | T classificationb | | T1 + T2 | 46 (67.6) | 5 | 19 | | 13 | 9 | 0.2851 | | T3 + T4 | 22 (32.4) | 2 | 6 | | 8 | 6 |
| | Regional lymph node metastasisb | | Negative | 30 (44.1) | 4 | 12 | | 7 | 7 | 0.5142 | | Positive | 38 (55.9) | 3 | 13 | | 14 | 8 |
| | Histopathologic gradea | | Well | 44 (53.0) | 3 | 12 | | 17 | 12 | 0.0143 | | Moderate + Poor | 39 (47.0) | 5 | 20 | | 8 | 6 |
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Statistically significant. a83 cases. b68 cases. |