Research Article

Antimicrobial Activity of Thermocycled Polymethyl Methacrylate Resin Reinforced with Titanium Dioxide and Copper Oxide Nanoparticles

Table 1

Means ± standard deviations, biofilm inhibition (%), and multiple comparisons of optical density of the study groups for bacteria species.

GroupsFactorsBacteria species
S. mutansS. sobrinusS. salivariusS. sanguis

2.5% TiO2Optical density0.70 ± 0.02cd1.66 ± 0.23a0.69 ± 0.00a0.51 ± 0.07a
Biofilm inhibition25%48%80%70%

7.5% TiO2Optical density0.42 ± 0.06bc1.78 ± 0.09a0.28 ± 0.01b0.27 ± 0.07a
Biofilm inhibition18%43.7%93%79%

2.5% CuOOptical density0.19 ± 0.03ab3.70 ± 0.21b0.58 ± 0.12ab0.50 ± 0.13a
Biofilm inhibition60%6%83%44%

7.5% CuOOptical density0.17 ± 0.07a0.34 ± 0.06c0.34 ± 0.06b0.18 ± 0.01a
Biofilm inhibition66%89%90%80%

ControlOptical density0.58 ± 0.08c3.00 ± 0.24b3.16 ± 0.09c0.99 ± 0.08b

Vertically within groups, different superscript lowercase letters indicate significant differences between groups in the same column ( ≤ 0.05).