Bacterial Colonization of the Condyle in Patients with Advanced Mandibular Osteoradionecrosis: Analysis of Hemimandibulectomy Specimens

Figure 3

Preoperative CT images of condyles (a–c) and results of hematoxylin and eosin staining (a’–c’) in mandibular condyles of patients 1, 2, and 4. Results of Gram staining of areas indicated with black dotted boxes are shown in enlarged images (a”–c”). Within the region of partial bone marrow hollowing, inflammatory cell infiltration (a’) and bacterial colonization (a”) are evident in condyle of patient 1. Within the region of cortical hollowing, chronic fibrosis (b) and bacterial colonization (b”) are evident near condyle of patient 2. Although fibrosis and fatty degeneration are evident in bone marrow area (c’), no bacterial colonization is evident (c”) in condyle of patient 4. Asterisks () indicate the articular surfaces of condyles. Scale bar = 20 μm.