Correlation between Clinical and Histopathological Diagnoses in Oral Cavity Lesions: A 12-Year Retrospective Study
Table 4
Frequency and concordance rate of clinical and histopathologic diagnosis in each category of lesions.
Lesion
Total cases
Concordance N (%)
Ulcerative, vesicular, and bullous lesions
Pemphigus vulgaris
46
34 (73.9%)
Pemphigoid
15
3 (20%)
Eosinophilic ulcers of tongue
9
3 (33.3%)
Traumatic ulcers
3
0 (0%)
Recurrent aphthous stomatitis
1
1 (100%)
Erythema multiform
1
1 (100%)
White and red lesions
Lichen planus
449
398 (88.6%)
Leukoplakia
63
49 (77.8%)
Oral erythroplakia
4
0 (0%)
Lupus erythematosus
2
0 (0%)
Hairy leukoplakia
1
0 (0%)
Pigmented lesions
Oral/Labial melanotic macule
14
11 (78.6%)
Inflammatory hyperpigmentation
6
0 (0%)
Melanocytic nevus
6
2 (33.3%)
Oral melanoacanthoma
4
2 (50%)
Malignant melanoma
3
1 (33.3%)
Melanosis
1
0 (0%)
Exophytic soft tissue lesions1
Reactive/Inflammatory lesions
1100
742 (67.4%)
Fibroma
361
247 (68.4%)
Pyogenic granuloma
252
137 (54.4%)
Mucocele
174
160 (91.9%)
Epulis fissuratum
125
109 (87.2%)
Peripheral giant cell granuloma
124
57 (46%)
Peripheral odontogenic fibroma
38
18 (47.4%)
Epulis granulomatosa
14
9 (64.3%)
Neurofibroma
12
5 (41.7%)
Benign tumoral lesions
83
43 (52%)
Oral papilloma
50
33 (66%)
Pleomorphic adenoma
15
5 (33.3%)
Lipoma
5
0 (0%)
Schwannoma
5
1 (20%)
Hemangioma
4
0 (0%)
Traumatic neuroma
2
2 (100%)
Lymphangioma
1
1 (100%)
Basal cell adenoma
1
1 (100%)
Malignant tumoral lesions
143
108 (75.5%)
Squamous cell carcinoma
132
104 (78.8%)
Basal cell carcinoma
3
1 (33.3%)
Lymphoma
3
0 (0%)
Mucoepidermoid carcinoma
3
1 (33.3%)
Adenoid cystic carcinoma
2
2 (100%)
Bone lesions2
Cystic lesions
861
669 (77.7%)
Radicular cyst
420
358 (85.2%)
Odontogenic keratocyst
184
115 (62.5%)
Dentigerous cyst
173
134 (77.4%)
Residual cyst
54
36 (66.7%)
Nasopalatine canal cyst
18
18 (100%)
Traumatic bone cyst
11
7 (63.6%)
Aneurysmal bone cyst
1
1 (100%)
Benign tumoral lesions
133
71 (53.4%)
Central giant cell granuloma
50
26 (52%)
Ameloblastoma
33
16 (48.5%)
Odontoma
15
13 (86.7%)
Osteoma
11
7 (63.6%)
Cementoblastoma
7
4 (57.1%)
Adenomatoid odontogenic tumor
7
1 (14.3%)
Central odontogenic fibroma
1
1 (100%)
Odontogenic myxoma
7
3 (42.9%)
Ameloblastic fibroma
1
0 (0%)
Malignant tumoral lesions
14
9 (64.3%)
Osteosarcoma
11
6 (54.5%)
Fibrosarcoma
2
2 (100%)
Chondrosarcoma
1
1 (100%)
Other
39
20 (51.2%)
1. Exophytic lesions were subdivided into two subgroups: reactive/inflammatory and tumoral lesions (malignant and benign tumors). 2. Bone lesions were subdivided into two subgroups: cystic and tumoral lesions (malignant and benign tumors). Bone samples that were not included in either cystic or tumoral lesion were named “other”. This category includes developmental lesions of bone (fibrous dysplasia, ossifying fibroma, and periapical cemento-osseous dysplasia).
