Taking 200 mg Vitamin C Three Times per Day Improved Extraction Socket Wound Healing Parameters: A Randomized Clinical Trial

Table 3

% reduction in mean wound size between the 2 extraction sites in the 600/1,500 group (600 mg vitamin C/d vs. 1,500 mg vitamin C/d).

Mean difference	% reduction of the extraction wound at the 600 mg vitamin C/d side	% reduction of the extraction wound at the 1,500 mg vitamin C/d side	value^a
Immediate and 7 days
Bucco-lingual	48.2	42.3	0.767
Mesio-distal	45.0	44.6	0.953
Depth	69.4	70.0	0.753
Immediate and 21 days
Bucco-lingual	58.1	56.4	0.953
Mesio-distal	52.7	53.0	0.674
Depth	86.6	83.0	0.237
7 days and 21 days
Bucco-lingual	20.2	22.0	0.674
Mesio-distal	14.1	13.8	1.000
Depth	53.0	41.1	0.160

SD, standard deviation. ^a value, Wilcoxon signed-rank test. .