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Author/Year/Country/Study design | Sample size | Interventions/protocols | Evaluations/follow-up | Findings |
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Flecha et al., [18, 24]/Brazil/RCT, Double-blind, split-mouth | 434 Teeth | TG - Super Bonder® CG - LLLT Protocol: 3x 48/48 hs | NRS: - Air spray = 4s - Tetrafluormethan spray (Endo Ice®) = 4s Baseline, 24 hr, 30, 90, and 180 days | Reduction in DH ≠ a significant. Within 24 hr better results were recorded for cyanoacrylate |
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Flecha et al., [18, 24]/Brazil/RCT, Double-blind, split-mouth -Pilot study | 34 Hemiarch | TG - Super Bonder® CG - LLLT Protocol: 3x 48/48 hs | NRS: - Air spray = 5s - Tetrafluormethan spray (Endo Ice®) = 5s Baseline, 24 hr, 30, and 120 days | TG = Endo-Ice: 24 hr ≠ significant TG = Air blast: 120 days ≠ significant CG = Endo-Ice: 120 days ≠ significant |
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Naregal and Raju [27]/Índia/NRCT | 45 Teeth 15 Patients | G1 (CG) = Distilled water G2 = Potassium oxalate 30% G3—N-butyl 2-cyanoacrylate Protocol: 1 min | VAS: - Tactile stimuli - Electrical stimulation Baseline, immediate and once a week for 12 weeks | Tactile stimulus: G2 and G3 = ≠ significant 7 weeks G2 = w/o DH until end Electrical stimulation: G2 and G3 = ≠ significant 6 weeks G3 = > DH reduction |
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de la Caridad Perez-Alvarez et al. [17]/Cuba/NRCT | 152 Patients | - Chlorhexidine 0,2% = 1 min - Tisuacryl® = 60s | Pain evaluation: Level 1 = absence Level 2 = pain remains 2, 4, 5 e 6 days after intervention | Treatment with Tisuacryl: was successful in 96.7% of patients: Severe DH = 81.5% Light/moderate = 100% |
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Santos et al. [25]/Brazil/NRCT | 655 Teeth 73 Patients | G1: Super Bonder® = 1 G2: Prime & Bond 2.1 = 1 G3: Super Bonder® = 4 G4: Prime & Bond 2.1 = 4 | - Mechanical stimuli = exploratory probe n 5 - Thermal stimuli = air spray/Endo Ice® Baseline, weekly, and 60 days | Groups 3 and 4: statistically significant results in DH reduction |
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Guimarães [26]/Brazil/NRCT | 60 Teeth 23 Patients | G1: Fluorniz® = 4 G2: Super Bonder® = 1 | - Mechanical stimuli = exploratory probe - Thermal stimuli = water spray/air spray 7/7 days - 3 weeks | Super Bonder® Group: 93.3% - DH reduction Fluorniz® Group: 90% - DH reduction |
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Javid et al. [28]/Iran/NRCT | 60 Patients | G1: NaF 33% = 6 G2: cyanoacrylate = 1 | - Air spray for 1s 24 hr and weekly (6x) | Cyanoacrylate group: 25 = immediate and continuous relief. Fluoride Group: 21 = had lower scores than initial |
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