Novel Herbal Therapeutic YH23537 Improves Clinical Parameters in Ligature-Induced Periodontal Disease Model in Beagle Dogs

Table 1

Baseline of clinical parameters after randomization.

Parameters	Control	Placebo	YH23537 75 mg	YH23537 300 mg	YH23537 900 mg	YH14642 1,000 mg
PI	0.83 ± 0.41	1.39 ± 0.85		1.50 ± 0.86		1.50 ± 0.71
GI	0.00 ± 0.00	2.28 ± 0.57	2.11 ± 0.32	2.33 ± 0.59	2.39 ± 0.70	2.17 ± 0.51
PD (mm)	1.81 ± 0.13	2.81 ± 0.41	2.58 ± 0.52	2.55 ± 0.23	2.57 ± 0.21	2.56 ± 0.23
CAL (mm)	0.00 ± 0.00
GR (mm)	−1.81 ± 0.13
BoP	0.22 ± 0.17					0.33 ± 0.34

Data represent the mean ± SD. , , and compared with the control group. compared with the placebo group.