| | Author, year | Country | Length of follow-up | Sample size | Age (SD) | Miller class | Control | Intervention | Evaluated outcomes | Finding |
| | Santamaria et al., 2017 [20] | Brazil | Baseline, 3 months, 6 months | 42 | 40.2 ± 9.6 years | Miller’s class I or II gingival recession in maxillary canine and premolar | TUN + CTG | CAF + CTG | CRC, REC-reduction, GRD, mRC, RES, KTT, KTW, PD, and VAS | CAF + CTG and TUN + CTG could
reduce GR and improve aesthetics in defects | | Tavelli et al., 2019 [21] | United States | From 6 months to 12 months | 67 | 18 years old | Miller class I or II and cairo (RT1) maxillary incisors, canines, or premolars | TUN + ADM | CAF + ADM | REC, PD, CAL, CRC, mRC, KTW, and GT | There was a significant gain in gingival margin
when GR was treated with ADM | | Ozenci et al., 2015 [19] | Turkey | Baseline and 12 months | 20 | 30.7 ± 5.9 years | Miller’s class I in maxillary or mandibular canines, premolars, or incisors | TUN + ADM | CAF + ADM | mRC, CRC, PI, GI, BoP, PD, CAL, RH, RW, GT, and KTH | Better clinical results were obtained with the combination of CAF + ADM although both techniques were effective in the treatment of GR | | Ramos et al., 2022 [16] | Brazil | Baseline and 6 months | 20 | 18–59 years | Miller class III | CAF + ADM | TUN + ADM | PD, rCAL, GR, KT, TKT, and GRA | Both CAF + ADM and TUN + ADM were effective in root coverage of GR | | Papageorgakopoulos et al., 2008 [17] | United States | After surger, patients were evaluated for 8 weeks, and then monthly until the end of the study period | 24 | 40 ± 13 years | Miller class I or II maxillary and mandibular canines and premolars | TUN + ADM | CAF + ADM | KTT, PD, GT, GR, and CA | Both CAF + CTG and TUN + CTG could
reduce GR |
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CAF, coronally advanced flap; TUN, tunnel technique; ADM, acellular dermal matrix; GR, gingival recession; CRC, complete root coverage; CAL, clinical attachment level; KTW, keratinized tissue width; PD, probing depth; REC, recession coverage; mRC, mean root coverage; RC, root coverage; GT, gingival thickness; CTG, connective tissue graft; KTT, keratinized tissue thickness; PPD, pocket probing depth; WKT, width of keratinized tissue; STT, soft tissue thickness; HKT, height of keratinized tissue: GI, gingival index; CEJ, connective junctional epithelium; VAS, visual analog scale; RES, root esthetic score; PI, plaque index; GI, gingival index; BoP, bleeding on probing; RH, recession height; RW, recession width; CA, creeping attachment; TKT, thickness of keratinized tissue; GRA, gingival recession area; rCAL, relative clinical attachment level; KT, width of keratinized tissue.
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