Pretreatment Carcinoembryonic Antigen Level Serves as a Potential Biomarker to Guide Adjuvant Radiotherapy in pT4N+ Colon Cancer Patients

Table 1

Comparison of clinicopathological features according to receipt of adjuvant radiotherapy, stratified by the CEA status.

Variable	Elevated CEA level			Normal CEA level
	Surgery + RT	Surgery		Surgery + RT	Surgery
Age (years)			<0.001			<0.001
≤60	104	1251		71	1270
>60	108	3217		80	2662
Sex			0.006			0.926
Male	115	1994		77	1990
Female	97	2474		74	1942
Histologic type			0.117			0.703
Adenocarcinoma	156	3259		110	2950
Mucinous	38	623		18	491
Signet ring cell	4	170		5	134
Other	14	416		18	357
Grade			0.047			0.338
G1 + G2	134	2564		88	2208
G3 + G4	69	1788		58	1651
Unknown	9	116		5	73
Tumor size			<0.001			0.003
<5 cm	57	1961		56	2018
≥5 cm	143	2326		89	1796
Unknown	12	181		6	118
N stage			0.007			0.394
N1	135	2422		91	2232
N2	77	2046		60	1700