Neutrophil and Monocyte CD64 and CD163 Expression in Critically Ill Neonates and Children with Sepsis: Comparison of Fluorescence Intensities and Calculated Indexes

Table 2

Median CD64 and CD163 MFI and indexes (i) for neutrophils and monocytes with 95% confidence interval (CI) in critically ill neonates and children at the time of suspected sepsis (day 0) and 24 hours later (day 1).

	Day 0			Day 1
	SIRS with sepsis	SIRS	P	SIRS with sepsis	SIRS	P
Neutrophils
CD64fMFI	83 (66–108)	44 (36–56)	.0000^*	100 (75–162)	47 (32–54)	.0000^*
CD64i	2.65 (2.02–4.03)	1.3 (1.06–1.78)	.0000^*	3.36 (2.27–4.68)	1.47 (1.07–1.78)	.0000^*
CD163MFI	65 (50–85)	47 (44–64)	.0463^*	80.5 (57–115)	50.5 (40.2–84.8)	.0056^*
CD163i	456 (423–548)	447 (381–491)	.2250	527 (486–621)	462 (426–528)	.0495^*
Monocytes
CD64MFI	251 (231–294)	168 (149–212)	.0000^*	307 (257–354)	195 (159–243)	.0001^*
CD64i		9.36 (7.94–11.2)	6.69 (5.6–7.28)	.0001^*	11 (8.39–13.4)	7.41 (6.43–8.22)
CD163MFI	2350 (1674–3942)	1451 (1234–1637)	.0063^*	3281 (2369–4093)	2483 (1927–2937)	.0439^*
CD163i	20080 (9330–27352)	9460 (7708–14893)	.0836	21136 (13636–32551)	20142 (15926–25366)	.9598

^*statistically significant differences, Unpaired Mann-Whitney test.