Th1 and Th2 Immune Response in Chronic Hepatitis B Patients during a Long-Term Treatment with Adefovir Dipivoxil

Table 4

Correlation between intracellular Th1/Th2 cytokines and ALT, AST, HBV DNA load, and HBsAg.

	IL-2% CD3+CD4+	IFN-γ% CD3+CD4+	TNF-α% CD3+CD4+	IL-4% CD3+CD4+	IL-10% CD3+CD4+
ALT
𝑅	−0.365	−0.402	−0.35	−0.386	−0.426
𝑃	<.0001	<.0001	<.0001	<.0001	<.0001
AST
𝑅	−0.376	−0.356	−0.351	−0.285	−0.461
𝑃	<.0001	<.0001	<.0001	<.0001	<.0001
HBVDNA
𝑅	−0.319	−0.382	−0.216	−0.479	−0.249
𝑃	<.0001	<.0001	0.0034	<.0001	0.007
HBsAg
𝑅	−0.245	−0.186	−0.173	−0.223	−0.152
𝑃	0.014	0.062	0.083	0.025	0.128