Metabolic Phenotype and Adipose Tissue Inflammation in Patients with Chronic Obstructive Pulmonary Disease

Table 3

Insulin sensitivity determined by euglycemic hyperinsulinemic clamp and insulin-induced serum-free fatty acids in patients with COPD.

Variable	Entire group	Group				𝑃 value
		Cachectic	Normal weight	Overweight	Obese
𝑀, mg·kg^−1·min^−1	5.00±2.74	7.48±2.22	6.42±2.65	3.81±1.84^*†	2.71±1.20^*†	<.001
𝑀/𝐼×100, mg·kg^−1·min^−1·μU^−1·mL	6.72±4.50	11.65±3.52	9.01±3.65	4.76±2.62^*†	2.33±1.01^*†‡	<.001
FFA, mmol·L^−1	0.11±0.05	0.07±0.03	0.09±0.04	0.12±0.06	0.14±0.05^*†	.004

* 𝑃<.05 versus cachectic group.
^†𝑃<.05 versus normal-weight group.
^‡𝑃<.05 versus overweight group.
𝑀: glucose uptake; 𝑀/ 𝐼: insulin sensitivity—glucose uptake to insulinemia ratio; FFA: free fatty acids.