Research Article

Oxidative Damage in Lymphocytes of Copper Smelter Workers Correlated to Higher Levels of Excreted Arsenic

Figure 2

Comparative effect of arsenic exposure on lipid peroxidation in blood samples from low- and high-exposure human populations. (a) Comparison of MDA distribution profile in blood samples isolated from low-As-exposure (control, 𝑛 = 3 1 ) and high-As-exposure ( 𝑛 = 5 0 ) human populations. Lipid peroxidation was assessed by plasma MDA concentration. The statistical analysis indicates significant differences between the two groups (test U-Mann-Whitney 𝑃 < . 0 0 0 1 ). (b) Correlation between MDA concentration and urinary excretion of As in the high As-exposure population ( 𝑛 = 5 0 ). The associations between the two variables were determined by 𝑅 -Pearson ( 𝑃 < . 0 0 0 1 ).
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(b)