Intravenous Sphingosylphosphorylcholine Protects Ischemic and Postischemic Myocardial Tissue in a Mouse Model of Myocardial Ischemia/Reperfusion Injury
Figure 4
The S1P3 lysophospholipid receptor is required for cardioprotection by SPC. Infarct size/area at risk was determined in S1P3-deficient mice and their matching wild-type controls (C57BL/6) after treatment with SPC (1.25 μg/g body weight).