Research Article

High-Mobility Group Box-1 Protein Serum Levels Do Not Reflect Monocytic Function in Patients with Sepsis-Induced Immunosuppression

Table 2

Correlation table of systemic HMGB-1 levels with markers of monocytic function.

HMGB-1 serum level
baselineday 3day 5day 7after therapy
(day 1)(day 9)

mHLA-DR expression- overall groupP=.65P=.61P=.12P=.31P=.38
r=0.08r=0.09r=0.27r=0.18r=0.16
- treatment groupP=.98P=.90P=.98P=.24P=.73
r=0.01r=-0.03r=0.01r=0.29r=0.09
- control groupP=.49P=.22P=.97P=.86P=.80
r=0.18r=0.31r=0.01r=-0.05r=0.07
ex vivo LP-Sinduced TNF-α release- overall groupP=.91P=.97P=.77P=.57P=.56
r=-0.02r=-0.01r=0.05r=-0.10r=0.11
- treatment groupP=.41P=.50P=.30P=.46P=.69
r=-0.20r=-0.17r=-0.25r=-0.18r=-0.11
- control groupP=.48P=.16P=.97P=.89P=.43
r=0.18r=0.36r=-0.01r=-0.03r=0.21