High-Mobility Group Box-1 Protein Serum Levels Do Not Reflect Monocytic Function in Patients with Sepsis-Induced Immunosuppression

Table 4

Correlation analysis of systemic HMGB-1 levels with indices of disease severity.

		HMGB-1 serum level
		baseline (day 1)	after therapy (day 9)	all samples (day 1 + 9)
APACHE II Score	- overall group	$P=.053$	$P=.32$	$P=.71$
		$r=-0.32$	$r=0.19$	$r=-0.05$
	- treatment group	$P=.34$	$P=.16$	$P=.34$
		$r=-0.23$	$r=0.36$	$r=-0.23$
	- control group	$P=.09$	$P=.51$	$P=.09$
		$r=-0.43$	$r=0.19$	$r=-0.43$
SOFA score	- overall group	$P=.90$	$P=.38$	$P=.42$
		$r=-0.02$	$r=-0.17$	$r=-0.1$
	- treatment group	$P=.58$	$P=.12$	$P=.58$
		$r=-0.14$	$r=-0.39$	$r=0.14$
	- control group	$P=.82$	$P=.55$	$P=.83$
		$r=-0.06$	$r=-0.17$	$r=-0.06$