Pro- and Anti-Inflammatory Cytokines during Immune Stimulation: Modulation of Iron Status and Red Blood Cell Profile

Table 3

Serum iron markers and soluble transferrin receptor for patients with elevated C-reactive protein and patients with normal C-reactive protein.

Normal laboratory values	Elevated CRP (n = 28); Geometric mean; 95% confidence interval	Normal CRP (n = 19); Geometric mean; 95% confidence interval	P-value
Serum iron; (10–30 μmol/L)	6.87; 5.11–9.22	7.89; 5.15–12.08	.57
Serum transferrin (2–3.6 g/L)	1.21; 1.04–1.41	2.33; 1.98–2.75	.000
Transferrin saturation (15–50% f, 20–50% m)	21.59; 14.90–31.26	14.34; 8.48–24.25	.18
Serum ferritin (11–306.8 μg/L f, 23.9–336.2 μg/L m)	928.70; 482.12–1788.95	44.97; 19.31–104.71	.000
Transferrin/log ferritin	0.43; 0.34–0.54	1.59; 1.07–2.38	.000
Soluble transferrin receptor (2.9–8.3 μg/mL)	7.41; 5.69–9.67	13.38; 9.30–19.24	.008
Soluble transferrin receptor/log ferritin	2.58; 1.94–3.43	9.14; 5.22–16.00	.000