Research Article

LPS Counter Regulates RNA Expression of Extracellular Proteases and Their Inhibitors in Murine Macrophages

Figure 2

Widespread increase in the MMP gene expression level following LPS treatment. The RNA expression of MMPs following LPS treatment of macrophage cultures was generally increased compared to vehicle stimulated cultures. The basal expression level of MMPs (0 hours) varied considerably and the most abundantly expressed MMP (MMP12) had a 20,000-fold higher expression level than the lowest detectable MMP (MMP3). Data were analyzed by a two-tailed Mann-Whitney test. * between LPS and vehicle stimulated cultures. for all groups.
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