Heat Shock Proteins in Tendinopathy: Novel Molecular Regulators

Figure 3

Overview of heat shock biology in tendinopathy. Schematic diagram illustrating the manner in which early tendinopathy may arise due to HSP release. An increase in stress that a tendon cell experiences results in the release of various inflammatory mediators and associated HSPs that interact to drive the tendon matrix toward a degenerative or reparative process.