Review Article
Mechanisms of Inflammation in Proliferative Vitreoretinopathy: From Bench to Bedside
Table 1
Outcomes of therapeutic agents used in animals to prevent proliferative vitreoretinopathy (PVR).
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PDGF: platelet-derived growth factor. ARC128: nonfunctional version of ARC127. P7: postnatal day 7. P12: postnatal day 12. inj.: injection. PBS: phosphate-buffered saline. OD: right eye. OS: left eye. GSA+ cells: ectopic cells in the inner retina staining positive for Griffonia simplicifolia lectin. totRD: total, pRD: partial, RD: retinal detachment. *statistically significant difference compared to control. mAb: monoclonal antibody. PDGFR: platelet-derived growth factor receptor. PRP: platelet-rich plasma. #S0–#S5: number of cases observed at a given Fastenberg Stage of PVR 0–5. d: day. ROS: reactive oxygen species. TGFα: transforming growth factor α. EGF: epidermal growth factor. HGF: hepatocyte growth factor. FGF-2: fibroblast growth factor 2. TGFβ: transforming growth factor β. IL-8: interleukin 8. IGF-1: insulin-like growth factor-1. Ref: Reference number. |