Role of Macrophage Migration Inhibitory Factor in the Proliferation of Smooth Muscle Cell in Pulmonary Hypertension

Figure 1

MIF expression in rat lung homogenates. (A) MIF expression was measured by RT-PCR before and after hypoxia exposure. There was a marked upregulation of MIF in the lungs from hypoxic rat (a). Bar graph showed MIF mRNA levels obtained from quantitative densitometry analysis (b). (B) Western blot analysis demonstrated that MIF protein was increased in rat lung homogenates after hypoxia exposure (a). Bar graph showed MIF protein levels obtained from quantitative densitometry analysis (b). 𝑛=5. ^∗𝑃<0.05 versus control.