Scutellarin Attenuates Hypertension-Induced Expression of Brain Toll-Like Receptor 4/Nuclear Factor Kappa B

Figure 1

Effect of scutellarin treatment on systolic blood pressure (SBP). Baseline systolic blood pressure (SBP) (mmHg) was similar among the four experimental groups. SBP was significantly increased in hypertensive groups compared with the sham-operated group. No significant difference in SBP was found in NS rats prior to treatment. However, SBP was significantly reduced with low- and high-dose scutellarin. ^∗𝑃<0.001 versus sham group; ^#𝑃>0.05, ^▴𝑃<0.001 versus NS group; ^♦𝑃<0.001, versus before treatment; ^▼𝑃>0.05, ^&𝑃<0.001 versus low-dose group.