Scutellarin Attenuates Hypertension-Induced Expression of Brain Toll-Like Receptor 4/Nuclear Factor Kappa B

Figure 4

Scutellarin attenuates hypertension-induced brain expression of NF-κB, TNF-α, IL-1β, and IL-18. Western immunoblot analysis for (a) NF-κB p65, (b) TNF-α, (c) IL-1β, and (d) IL-18 in the rat cortex and striatum. Treatment with scutellarin significantly reduced the expression of these inflammatory markers in a dose-dependent manner. ^∗𝑃<0.001 versus sham group; ^#𝑃<0.05, ^◆𝑃<0.001 versus NS group; ^&𝑃<0.001 versus low-dose group.

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