Research Article

High Sugar Intake and Development of Skeletal Muscle Insulin Resistance and Inflammation in Mice: A Protective Role for PPAR-δ Agonism

Figure 3

Effects of two dietary regimens either normal (control) or a diet enriched with 15% HFCS solution (HFCS) on GLUT-4 and GLUT-5 expression (resp., (a) and (c)) and membrane translocation (resp., (b) and (d), original magnification: 400x) in the gastrocnemius of mice treated with GW0742 (1 mg/kg/day, ; ). Densitometric analysis of the bands is expressed as relative optical density (O.D.), corrected for the corresponding tubulin, and normalized using the related control band. Data are of three separate experiments. * versus HFCS.
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