Urinary Eosinophil Protein X in Childhood Asthma: Relation with Changes in Disease Control and Eosinophilic Airway Inflammation

Table 1

Characteristics of the 205 children at baseline.

Age (y)	10.4 [6.4–16.8]
Gender (m/f)	118/87
Daily dose fluticasone 200 𝜇g/500 𝜇g	116/89
uEPX (𝜇g/mmol creatinine) (𝑛=180)	184 (2–3114)
Symptom-free days (%)	50 (0–100)
FEV1 (% pred)	97 (56–136)
PD20 methacholine (𝜇g)	72 (1–>1570.0^#)
Sputum eosinophils (%) (𝑛=49)^†	1 (0–72)

Values are median (range).
FEV₁: forced expiratory volume in 1 second; PD₂₀ methacholine: provocative dose of methacholine causing FEV₁ fall 20% from baseline.
^#12 children had not reached the 20% fall at the highest dose of 1570 𝜇g.
^†79 patients had a total of 127% eos measurements combined with an uEPX measurement, and in 49 of these a baseline measurement was available.
Baseline characteristics form part of this group have been published previously in a cross-sectional study by Nuijsink et al. [13].