Urinary Eosinophil Protein X in Childhood Asthma: Relation with Changes in Disease Control and Eosinophilic Airway Inflammation

Table 2

Correlations between uEPX and clinical markers of asthma.

		𝑟	𝑃 value
	T0	−0.04	0.96
Symptom-free days (%)	T1	0.03	0.68
	T2	0.09	0.34
	T0	−0.18	0.01
FEV1 (% pred)	T1	−0.25	<0.01
	T2	−0.22	0.02
	T0	0.19	0.19
Sputum eosinophils (%)	T1	0.19	0.20
	T2	0.51	<0.01
	T0	−0.14	0.08
PD20 methacholine (𝜇g)	T1	−0.20	0.02
	T2	−0.14	0.14

T0: at baseline; T1: after a treatment period of 1 year; T2: after a treatment period of 2 years; FEV₁: forced expiratory volume in 1 second. Numbers evaluated for sputum eosinophils at T0, T1, and T2 are 49, 45, and 33, respectively. Data shown represent Spearman rank correlation coefficients.
Correlations at baseline (T0) in part of this group have been published previously in a cross-sectional study (Nuijsink et al. [13]).