The Role of Glucocorticoid Receptors in Dexamethasone-Induced Apoptosis of Neuroprogenitor Cells in the Hippocampus of Rat Pups

Table 2

Effects of dexamethasone and RU486 on D1D2 rat pup body weight and brain weight.

Treatment	Body weight, Mean ± SE, g (𝑁=6)	Brain weight, Mean ± SE, g, (𝑁=6)
NS	7.75±0.04	0.314±0.004
Dex	6.75±0.08 *	0.293±0.004
DMSO	7.50±0.09	0.309±0.004
RU486	7.16±0.08	0.312±0.004
DMSO/Dex	6.83±0.04	0.301±0.004
RU486/Dex	7.08±0.03	0.319±0.004

𝑁: number of pups.
Compared pups injected with dexamethasone (Dex) and normal saline (NS) by using Wilcoxon rank sum test, *𝑃<0.05.
D1D2: administration on postnatal day 1 and sacrificed on day 2; RU486: mifepristone;
DMSO: dimethyl sulfoxide; DMSO/Dex: dimethyl sulfoxide plus dexamethasone;
RU486/Dex: mifepristone plus dexamethasone.