Downregulation of NOX4 Expression by Roflumilast N-Oxide Reduces Markers of Fibrosis in Lung Fibroblasts
Figure 3
Effect of BLM and RNO on 8-epi-PGF2α release in HLF. Levels of F2-isoprostanes (8-epi-PGF2α) were determined by an enzyme immunoassay kit in the media of HLF from 3 donors treated with BLM (50 mU/mL) for 24 h, in presence or absence of RNO (2 nM). Data are mean SD of 3 experiments. versus control (C); versus BLM.
