The Role of T Cell Immunoglobulin Mucin Domains 1 and 4 in a Herpes Simplex Virus-Induced Behçet’s Disease Mouse Model

Figure 2

The frequencies of Tim-4⁺ cell phenotypes in normal healthy, BDN and Behçet’s disease (BD) mice. The frequencies of Tim-4⁺ cells in BD mice were compared to Nor and BDN mice by FACS analysis in (a) lymph nodes, (b) spleen, (c) PBMCs, and (d) peritoneal macrophages. The expression of CD11b⁺Tim-4⁺ and CD11c⁺Tim-4⁺ cells in BD mice were also compared to those in Nor and BDN mice in (e) lymph nodes and (f) spleen (𝑛=5–17) (**𝑃<0.05, ***𝑃<0.01, ****𝑃<0.001) Nor: normal healthy mice, BDN: BD normal mice.

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