Research Article

Transforming Growth Factor β1 Genotypes in Relation to TGFβ1, Interleukin-8, and Tumor Necrosis Factor Alpha in Induced Sputum and Blood in Cystic Fibrosis

Table 1

Patients characteristics.

CF patientsControls
( )( )
Median

ΔF 508 (homozygous)+
Age (years)20.527.5
Sex (m/f)(14/10)(3/5)
BMI (kg/m2)20.421.6
P. aeruginosa + 9
Shwachman score75
FEV1 (% predicted)83
MEF 25 (% predicted)36.7
VC (% predicted)84.9

ΔF 508 (homozygous): homozygous for the ΔF 508 mutation; m: male; f: female; P. aeruginosa +: Pseudomonas aeruginosa colonization; FEV1 (% predicted): forced expiratory volume in 1 s in % predicted; MEF 25 (% predicted): maximum expiratory flow at 25% of forced vital capacity in % predicted; VC (% predicted): vital capacity in % predicted.