Immune Activation, Immunosenescence, and Osteoprotegerin as Markers of Endothelial Dysfunction in Subclinical HIV-Associated Atherosclerosis

Table 2

Multivariate analysis.

	OR	95% CI	value
Age	1.008	1.005–1.011	<0.001
Sex	1.045	0.980–1.115	0.185
Smoke	1.002	0.947–1.060	0.942
Time of diagnosis	1.002	0.998–1.005	0.305
PI exposure	1.050	0.992–1.111	0.009
Cholesterol total	1.000	0.999–1.003	0.934
Cholesterol HDL	1.000	0.997–1.003	0.952
Cholesterol LDL	1.000	0.999–1.001	0.651
Triglycerides	0.999	0.999-1.000	0.172
OPG	0.998	0.990–1.006	0.632
IL-6	1.000	0.999–1.001	0.744
CD4+ nadir	0.999	0.999-1.000	0.264
CD4+ current	1.000	0.998–1.001	0.478
CD4+ HLADR+ CD38+	1.004	0.985–1.023	0.692
CD8+ HLADR+ CD38+	1.234	1.006–1.042	0.011
CD4+ CD28− CD57+	0.993	0.987–1.000	0.063
CD8+ CD28− CD57+	1.008	1.004–1.011	<0.001

OR: odd ratio; CI: confidence interval; PI: protease inhibitor; HDL: high density lipoprotein; LDL: low density lipoprotein OPG: osteoprotegerin; IL-6: interleukin-6.