Niacin Inhibits Vascular Inflammation via Downregulating Nuclear Transcription Factor-κB Signaling Pathway

Figure 8

Niacin upregulated apoA I level in plasma of guinea pigs fed high fat diet. HDL (density = 1.09–1.24 g/mL) was separated from plasma of guinea pigs by sequential ultracentrifugation. The SDS-PAGE was performed on 15% SDS polyacrylamide gel, and the apolipoproteins were stained with coomassie brilliant blue. Densitometric quantitation of SDS-PAGE image was analyzed by Image-Pro Plus software. (a) shows the representative SDS-PAGE image of HDL. (b) shows the relative level of apoA I in plasma by densitometric quantitation. Data are presented as mean ± SD of at least three independent experiments. ^#𝑃<0.05 versus CD group; ^∗∗𝑃<0.01 versus HFD group.

(a)

(b)