Relationship of MMP-14 and TIMP-3 Expression with Macrophage Activation and Human Atherosclerotic Plaque Vulnerability

Figure 5

Immunohistochemical staining of carotid plaque sections for (a) 4′,6-diamidino-2-phenylindole (DAPI), (b) NFκB, (c) TIMP-3, and (d) merged, demonstrating that the percentage of TIMP-3 positive FCMs with no nuclear NFκB was significantly greater (, ) compared to cytoplasmic or nuclear NFκB staining, as depicted in adjoining graph (e).

(a)

(b)

(c)

(d)

(e)