Chrysophanol Inhibits NALP3 Inflammasome Activation and Ameliorates Cerebral Ischemia/Reperfusion in Mice

Figure 6

Immunohistochemical staining of NALP3, ASC, caspase-1, and IL-1β in the cerebral cortex at 24 h after ischemia (400x magnification). As compared with tMACO and Vehicle groups, the expression of NALP3, caspase-1, and IL-1β was significantly reduced in CHR-H and CHR-M groups, but the expression of ASC remained unchanged.