Bronchoalveolar Lavage Fluid IFN- Th17 Cells and Regulatory T Cells in Pulmonary Sarcoidosis
Figure 4
The relationship of Th1, IFN-γ + Th17, and FoxP3+ CD4+ T cells in bronchoalveolar lavage fluid. (a) There was a highly significant correlation between fractions of IFN-γ + Th17 cells and Th1 cells (IFN-γ + CD4+) (, Spearman’s rho = 0.75, and ). Black and grey lines represent linear regression lines with 95% CI. (b) The IFN-γ + Th17/FoxP3+ CD4+ T cell ratio was markedly elevated in patients with sarcoidosis compared to other DPLDs or healthy control subjects. DPLD: diffuse parenchymal lung disease; HC: healthy control subjects.
