Plasma proteins expression as a function of MECP2 mutations in girls with classical Rett syndrome. (a) All MECP2 mutations, (b) R306C mutation (milder form), (c) T158M mutation (intermediate severity), (d) and (e) correspond to R168X and large deletions (severe forms), respectively. Data are compared to matched healthy controls and expressed as box-and-whiskers plots. Results of Kruskal-Wallis ANOVA are indicated.
