Research Article

Subclinical Inflammatory Status in Rett Syndrome

Figure 5

Predicted protein-protein interaction networks (PPI) created by STRING 9.05. Each circle represents an individual protein with the recognized abbreviated name. (a) Confidence PPI in which the thickness of the lines shows how strong the interactions are (threshold: 0.4, medium confidence). Positive, negative APR proteins and immune response proteins are highlighted in three different ellipsis. CD79A is represented with grey colour to indicate an unidentified protein by MS but helpful for linking IGHG2 with HPT. (b) Evidence PPI in which the colour of the lines represent the types of evidence which characterized the protein-protein association. Code lines: green: neighborhood, brown: coexpression, pink: experiments, sky-blue: databases, olive green: textmining. (c) Actions PPI of all proteins in which the different colour of the lines represent the mode of protein actions. Code lines: black: reaction, blue: binding.
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(c)