Clinical Study

Inflammatory Lung Disease in Rett Syndrome

Figure 3

Lymphocytic bronchiolitis and desquamative alveolitis in Mecp2 null mice. (a) Wild-type mouse lung: normal histological features (magnification 25x), (b) Mecp2 null mouse: peribronchiolar lymphocyticinfiltrate (magnification 50x), (c) Mecp2 null mouse lung: desquamative alveolitis with mild amount of alveolar exudate (50x), and (d) Mecp2 null mouse lung: terminal bronchiolitis at higher magnification (200x) lymphocytes and histiocytes infiltrates outside and inside thickened terminal bronchioles, with a resulting picture of lymphocytic bronchiolitis.
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(a)
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(b)
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(c)
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(d)