CD226 rs763361 Is Associated with the Susceptibility to Type 1 Diabetes and Greater Frequency of GAD65 Autoantibody in a Brazilian Cohort

Table 4

Allele and genotype frequencies of CD226 rs763361 variant in patients with type 1 diabetes and controls stratified by gender.

Variant; rs763361	Gender	T1D; 𝑛 (%)	Controls; 𝑛 (%)	OR	CI	𝑃
Genotype/allele
TT	Female	111 (35.1)	50 (21.9)	1.928	1.30–2.84	0.0012
TC + CC		205 (64.9)	178 (78.1)
T		360 (57.0)	227 (49.8)	1.335	1.04–1.70	0.0224
C		272 (43.0)	229 (50.2)
TT	Male	67 (31.2)	102 (28.2)	1.154	0.79–1.66	0.504
TC + CC		148 (68.8)	260 (71.8)
T		233 (54.2)	386 (53.3)	1.036	0.81–1.31	0.8213
C		197 (45.8)	338 (46.7)

𝑃 values were determined by chi square test; OR: odds ratio; IC: confidence interval; critical 𝑃was corrected by the Bonferroni’s method <0.025.