Clinical Study

Impact of STAT/SOCS mRNA Expression Levels after Major Injury

Figure 2

Posttraumatic STAT 3 mRNA expression profiles after major trauma in all patients (a), depending on injury severity (NISS, (b)) and depending on outcome (survival > 90 days, (c)), * SNK-test. STAT 3 mRNA expressions showed increasing expression levels posttraumatically with a significant maximum level 6 h after the traumatic event in all patients ( ). STAT 3 mRNA expressions were lower in patients with a NISS between 41 and 75 points compared to patients with a NISS less than 41 points. Nonsurvivors showed a higher STAT 3 expression level within the whole posttraumatic period without significant differences.
749175.fig.002a
(a)
749175.fig.002b
(b)
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(c)