Imbalance between IL-17A-Producing Cells and Regulatory T Cells during Ischemic Stroke

Figure 2

The proportion of IL-17A-producing cells was increased in IS patients. (a) Representative results from the FCM analysis of CD3⁺CD4⁺IL-17A⁺ (Th17) cells among the total CD4⁺ T cell population in IS patients compared with controls. (b) The statistical analysis of the Th17 proportions in 30 control subjects and 50 IS patients at 7 and 28 days after stroke. (c) Representative results from the FCM analysis of inflammatory cells obtained from control subjects and IS patients. The percentage of IL-17A⁺CD3⁺γ δ⁺ T cells among the total CD4⁺ T cell population is indicated. (d) Statistical analysis of the results from the FCM analysis of the proportions of IL-17A⁺CD3⁺γ δ⁺ T cells in the blood samples obtained from the 30 control subjects and 50 IS patients at 7 and 28 days after stroke. **𝑃<0.01 and ***𝑃<0.001, compared with the controls.

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