Imbalance between IL-17A-Producing Cells and Regulatory T Cells during Ischemic Stroke
Figure 3
The proportion of CD4+CD25+FOXP3+ Tregs was reduced in IS patients. (a) Representative results from the FCM analysis of the samples obtained from control subjects and IS patients. The percentage of CD4+CD25+FOXP3+ T (Treg) cells among the total CD4+ T cell population is indicated. (b) Statistical analysis of the results obtained from the FACS analysis of the samples from 30 control subjects and 50 IS patients at 7 and 28 days after stroke. (c) The FOXP3 mRNA expression levels in the PBMCs obtained from various groups were analyzed using real-time PCR, and the values were normalized to GAPDH. * and ***, compared with the controls. IS-1W = 1 week after IS; IS-4W = 4 weeks after IS.
