Local Inflammation in Fracture Hematoma: Results from a Combined Trauma Model in Pigs

Table 2

Comparison of serum and fracture hematoma concentrations on 14 h, 24 h, and 48 h.

	14 h	24 h	48 h
Serum IL-6 (pg/mL)	62.35 ± 38.12	71.95 ± 54.76	79.69 ± 58.59
Hematoma IL-6 (pg/mL)	3631.65 ± 2992.31	2725.91 ± 2370.57	1120.99 ± 1561.31
value	0.002	0.002	0.002
Serum IL-8 (pg/mL)	148.90 ± 25.85	161.78 ± 32.92	139.71 ± 34.44
Hematoma IL-8 (pg/mL)	658.29 ± 84.11	676.30 ± 181.66	877.69 ± 491.47
value	0.002	0.002	0.002
Serum IL-10 (pg/mL)	64.56 ± 41.83	64.55 ± 37.31	59.50 ± 30.24
Hematoma IL-10 (pg/mL)	245.57 ± 131.97	262.10 ± 163.15	271.47 ± 193.26
value	0.004	0.002	0.003
Serum HMGB1 (ng/mL)	2.2 ± 1.54	4.8 ± 3.9	3.01 ± 3.21
Hematoma HMGB1 (ng/mL)	573.5 ± 504.35	351.89 ± 152.79	246.79 ± 135
value	0.008	0.005	0.003
Serum HSP70 (ng/mL)	47.04 ± 40.07	56.06 ± 42.95	75.96 ± 59.36
Hematoma HSP70 (ng/mL)	87.17 ± 95.82	84.75 ± 99.81	130.61 ± 256.02
value	n.s.	n.s.	n.s.