Rapid Exercise-Induced Mobilization of Dendritic Cells Is Potentially Mediated by a Flt3L- and MMP-9-Dependent Process in Multiple Sclerosis

Figure 3

Induction of Flt3L and MMP-9 upon physical exercise. The serum level of Flt3L and MMP-9 was measured by means of ELISA in healthy controls (green dots) and MS patients (red dots). Results are shown as mean concentration ± SEM. Significance () in the complete population of both patients and controls is annotated by black lines, while green and red lines annotate significance in controls and patients, respectively. Abbreviations used are as follows: MS: multiple sclerosis; Flt3L: Fms-related tyrosine kinase 3 ligand; MMP: matrix metalloproteinase; before: measurement before the exercise test; after: measurement immediately after the test; 2 h: measurement 2 hours after the test; and SEM: standard error of the mean.